i2X aims to support the digital transformation of healthcare systems by improving how health data is exchanged — both within national borders and in cross-border interactions with the EU — without adding burden to healthcare professionals. Through in-service testing at demonstration sites in 12 EU Member States, i2X will show how digital tools can enable better care, better outcomes, and a more connected health ecosystem.
Co-funded by the European Union, i2X contributes directly to the vision and goals of the European Health Data Space (EHDS) and supports the rollout of MyHealth@EU services.

The i2X project – which stands for “Intelligent” Implementation of the European Electronic Health Record Exchange Format (EEHRxF) – will, for the first time, connect electronic health record systems across Europe.
UpHill is leading the consortium. The goal is to enable seamless access and sharing of health data across borders, ensuring better healthcare for patients who travel or live in different EU countries. The project will also strengthen care coordination across the EU, making healthcare systems more resilient. Key benefits include reducing costs and inefficiencies caused by duplicate medical procedures and tests while minimising risks associated with missing clinical information.
In practice, the project aims to ensure that different health information systems used across Europe can communicate with each other, meaning they can store, exchange, and interpret health data using a common language.
Over the next four years, the initiative will launch 35 pilot projects in five key areas: e-prescriptions, lab and test results, patient summaries, medical imaging, and discharge reports. A total of 12 EU Member States – including the Netherlands, Belgium, Cyprus, Czechia, Finland, France, Germany, Greece, Ireland, Italy, Portugal, and Spain- will participate. Most will run pilot projects, some incorporating Artificial Intelligence-based technologies.